Methyl gallate
CAS No. 99-24-1
Methyl gallate( Gallincin | NSC 363001 )
Catalog No. M19302 CAS No. 99-24-1
Methyl gallate is a reverse transcriptase inhibitor with antioxidant, anti-HIV-1 and HIV-1 enzyme inhibition activities.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameMethyl gallate
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NoteResearch use only, not for human use.
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Brief DescriptionMethyl gallate is a reverse transcriptase inhibitor with antioxidant, anti-HIV-1 and HIV-1 enzyme inhibition activities.
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DescriptionMethyl gallate is a reverse transcriptase inhibitor with antioxidant, anti-HIV-1 and HIV-1 enzyme inhibition activities.
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In VitroThe growth of A. viscosus is inhibited completely by a low dose of Methyl gallate (MIC=1 mg/mL). S. mutans and . sobrinus show intermediate sensitivity to Methyl gallate (MIC=2-4 mg/mL), whereas the growth of Lactobacillus spp. is inhibited completely at a relatively high concentration (MIC=8 mg/mL). Methyl gallate, in a concentration of 100 mM, could alleviate lipid peroxidation of the cells exposed to a short-term H2O2 treatment. In addition, Methyl gallate-treated cells could prevent intracellular glutathione (GSH) from being depleted following an exposure of H2O2 (8.0 mM) for a 3 h period. Methyl gallate inhibits Treg cell-suppressive effects on effector CD4+ T cells and Treg migration toward tumor environment. Furthermore, forkhead box P3 (Foxp3) expression is also significantly decreased by methyl gallate.
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In Vivo——
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SynonymsGallincin | NSC 363001
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PathwayOthers
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TargetOther Targets
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RecptorReverse Transcriptase
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number99-24-1
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Formula Weight184.14
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Molecular FormulaC8H8O5
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 160 mg/mL; 868.86 mM
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SMILESCOC(=O)c1cc(c(c(c1)O)O)O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Wang CR,et al. Environ Toxicol Pharmacol. 2014 Mar;37(2):626-37.
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